4-Methoxy-m-phenylendiamin - 4-Methoxy-m-phenylendiamin

Structural formula
Structural formula of 4-methoxy-m-phenylenediamine
Name 4-Methoxy-m-phenylendiamin
other names
  • 2,4-Diaminophenylmethylether
  • 3-Amino-4-methoxyanilin
  • 3-Amino-p-anisidin
  • 2,4-Diamino-1-methoxybenzol
  • 2,4-Diaminoanisol
  • 4-MMPD
Sum formula C 7 H 10 N 2 O
Brief description

colorless solid [1] [2]

External identifiers / databases
CAS number
EC number 210-406-1
ECHA-InfoCard 100.009.461
PubChem 11976
ChemSpider 11481
Wikidata Q20983436
Molar mass 138.17 g · mol −1
Physical state


Melting point

67–68 °C[1]

  • easily soluble in water [1]
  • soluble in water and ethanol (sulfate) [3]
safety instructions
GHS hazardous substance labeling from Regulation (EC) No. 1272/2008 (CLP) , [4] possibly extended [1]
08 - Dangerous to health 07 - Warning 09 - Dangerous for the environment


H and P phrases H: 302​‐​341​‐​350​‐​411
P: 201​‐​273​‐​281​‐​308+313 [1]
Toxicological data

460 mg·kg−1 (LD50, Ratte, oral)[1]

As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

4-methoxy- m -phenylenediamine , short 4-MMPD , is a chemical compound from the group of substituted Anisidine .

Extraction and presentation

4-methoxy- m- phenylenediamine was first prepared in 1913 by reducing 2,4-dinitroanisole with iron and acetic acid . [5]


4-methoxy- m- phenylenediamine is a colorless solid that is easily soluble in water. The sulfate is yellowish to purple in color. [1] [6]


4-methoxy- m- phenylenediamine and its sulfate have been used as an ingredient in hair and fur dyes. [6] It is also used as an intermediate in the manufacture of other dyes. [3]

Individual evidence

  1. a b c d e f g h Entry on 4-methoxy-m-phenylenediamine in the GESTIS substance database of the IFA , accessed on January 10, 2017(JavaScript required) .
  2. Entry on 2,4-diaminoanisole in the Hazardous Substances Data Bank , accessed December 29, 2016.
  3. a b Barry Leonard: Eighth Annual Report on Carcinogens. DIANE Publishing, 1999, ISBN 0-7881-8396-6, S. 88 ( limited preview in Google Book search).
  4. Entry on 4-methoxy-m-phenylenediamine in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on December 29, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
  5. International Agency for Research on Cancer, World Health Organization: Some Thyrotropic Agents. World Health Organization, 2001, ISBN 978-92-832-1279-9, S. 624 ( limited preview in Google Book search).
  6. a b Richard P. Pohanish: Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens. William Andrew, 2011, ISBN 978-1-4377-7869-4, S. 872 ( limited preview in Google Book search).